Ski3 Polyclonal Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bs-51094r-150ug |
| Product Name | Ski3 Polyclonal Antibody |
| Applications |
WB
IF
|
| Reactivity | Human |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | Polyclonal antibody raised in rabbit against human SKI3, using a recombinant protein |
| Clonality | Polyclonal |
| Isotype | Not determined |
| Concentration | 3ug/ul |
| Purification | Protein G purified polyclonal antibody in PBS containing 0.05% azide and 0.05% ProClin 300 |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C for 12 months. |
| Target | |
| Gene ID | 852659 |
| Swiss Prot | Q02793 |
| Synonyms | Antiviral protein SKI8, SKI8, Superkiller protein 8, REC13 |
| Background | Involved in double-strand break (DSB) formation during meiotic recombination through stabilization of SPO11 association with meiotic chromosome and helping SPO11 to recruit other DSB proteins like REC102 and REC104 to meiotic chromosomes. Also component of the SKI complex involved in 3'-mRNA degradation pathway. Represses dsRNA virus propagation by specifically blocking translation of viral mRNAs, perhaps recognizing the absence of CAP or poly(A). Essential for controlling the propagation of M double-stranded RNA (dsRNA) and thus for preventing virus-induced cytopathology. |
| Application Dilution | |
| WB | 1:300-5000 |
| IF | |