CCDC39 Polyclonal Antibody

$Lane 1: DU145 cell lysates probed with CCDC39 Polyclonal Antibody, Unconjugated (bs-8096R) at 1:1000 dilution and 4\u02daC overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37\u02daC.$

Lane 1: DU145 cell lysates probed with CCDC39 Polyclonal Antibody, Unconjugated (bs-8096R) at 1:1000 dilution and 4\u02daC overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37\u02daC.

$Lane 1: HL-60 cell lysates probed with CCDC39 Polyclonal Antibody, Unconjugated (bs-8096R) at 1:1000 dilution and 4\u02daC overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37\u02daC.$

Lane 1: HL-60 cell lysates probed with CCDC39 Polyclonal Antibody, Unconjugated (bs-8096R) at 1:1000 dilution and 4\u02daC overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37\u02daC.

Applications

WB
ELISA

Reactivity

Human

Predicted Reactivity

Mouse
Rat
Cow
Horse
Rabbit

Overview
Catalog #	bs-8096R
Product Name	CCDC39 Polyclonal Antibody
Applications	WB ELISA
Reactivity	Human
Predicted Reactivity	Mouse, Rat, Cow, Horse, Rabbit
Specifications
Conjugation	Unconjugated
Host	Rabbit
Source	KLH conjugated synthetic peptide derived from human CCDC39
Immunogen Range	651-750/941
Clonality	Polyclonal
Isotype	IgG
Concentration	1ug/ul
Purification	Purified by Protein A.
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition	Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID	339829
Subcellular location	Cytoplasm
Synonyms	CCD39_HUMAN; Ccdc39; Coiled-coil domain-containing protein 39.
Background	Required for assembly of dynein regulatory complex (DRC) and inner dynein arm complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Not required for outer dynein arm complexes assembly.Tissue specificity:Mainly expressed in nasal brushings and, to a lesser extent, in lungs and testis.Involvement in disease:Defects in CCDC39 are the cause of primary ciliary dyskinesia type 14 (CILD14) . A disorder characterized by abnormalities of motile cilia. Respiratory infections leading to chronic inflammation and bronchiectasis are recurrent, due to defects in the respiratory cilia; reduced fertility is often observed in male patients due to abnormalities of sperm tails. Half of the patients exhibit randomization of left-right body asymmetry and situs inversus, due to dysfunction of monocilia at the embryonic node. Primary ciliary dyskinesia associated with situs inversus is referred to as Kartagener syndrome.
Application Dilution
WB	1:300-5000
ELISA	1:500-1000