TMEM74 Polyclonal Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bs-9922R |
| Product Name | TMEM74 Polyclonal Antibody |
| Applications |
WB
ELISA
IHC-P
IHC-F
IF
|
| Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human TMEM74 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles. |
| Target | |
| Gene ID | 157753 |
| Synonyms | TMEM 74; TMEM-74; NET36; HGNC; transmembrane protein 74; transmembrane protein-74; TMM74_HUMAN. |
| Background | TMEM74 is a 305 amino acid protein encoded by a gene mapping to human chromosome 8. Made up of nearly 146 million bases, chromosome 8 encodes about 800 genes. Translocation of portions of chromosome 8 with amplifications of the c-Myc gene are found in some leukemias and lymphomas, and typically associated with a poor prognosis. Portions of chromosome 8 have been linked to schizophrenia and bipolar disorder. Trisomy 8, also known as Warkany syndrome 2, most often results in early miscarriage but is occasionally seen in a mosaic form in surviving patients who suffer to a varying degree from a number of symptoms including retarded mental and motor development, and certain facial and developmental defects. WRN is a DNA helicase encoded by chromosome 8 and shown defective in those with the early aging disorder Werner syndrome. Chromosome 8 is also associated with Pfeiffer syndrome, congenital hypothyroidism and Waardenburg syndrome. |
| Application Dilution | |
| WB | 1:300-5000 |
| ELISA | IHC-P1:200-400 |
| IHC-P | IFIHC-P1:50-200 |
| IHC-F | |
| IF | |