TLE1 (1C1) Monoclonal Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bsm-51112M |
| Product Name | TLE1 (1C1) Monoclonal Antibody |
| Applications |
WB
ELISA
|
| Reactivity | Human |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Mouse |
| Source | This TLE1 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 199-228 amino acids from the Central region of human TLE1. |
| Clonality | Monoclonal |
| Clone # | 1C1 |
| Isotype | IgG1 |
| Concentration | 0.5ug/ul |
| Purification | Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C for 12 months. |
| Target | |
| Gene ID | 7088 |
| Swiss Prot | Q04724 |
| Synonyms | ESG; ESG1; GRG1; Transducin-like enhancer protein 1; E(Sp1) homolog; Enhancer of split groucho-like protein 1; TLE1 |
| Background | Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG. |
| Application Dilution | |
| WB | 1:300-5000 |
| ELISA | |