TLE4 (4C4) Monoclonal Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bsm-51128M |
| Product Name | TLE4 (4C4) Monoclonal Antibody |
| Applications |
WB
|
| Reactivity | Human |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Mouse |
| Source | This TLE4 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 262-290 amino acids from the Central region of human TLE4. |
| Clonality | Monoclonal |
| Clone # | 4C4 |
| Isotype | IgM |
| Concentration | 0.5ug/ul |
| Purification | Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C for 12 months. |
| Target | |
| Gene ID | 7091 |
| Swiss Prot | Q04727 |
| Synonyms | ESG; BCE1; ESG4; GRG4; BCE-1; Grg-4; E(spI); Transducin-like enhancer protein 4; Groucho-related protein 4; TLE4; KIAA1261 |
| Background | Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by PAX5, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Essential for the transcriptional repressor activity of SIX3 during retina and lens development and for SIX3 transcriptional auto-repression (By similarity). |
| Application Dilution | |
| WB | 1:300-5000 |