CBX8 (12C7) Monoclonal Antibody

$Lane 1: A549 lysates; Lane 2:HeLa lysates; probed with CBX8 (12C7) Monoclonal Antibody, unconjugated (bsm-51407M) at 1:1000 overnight at 4\u00b0C followed by a conjugated secondary antibody for 60 minutes at 37\u00b0C.$

Lane 1: A549 lysates; Lane 2:HeLa lysates; probed with CBX8 (12C7) Monoclonal Antibody, unconjugated (bsm-51407M) at 1:1000 overnight at 4\u00b0C followed by a conjugated secondary antibody for 60 minutes at 37\u00b0C.

Applications

Reactivity

Human

Overview
Catalog #	bsm-51407M
Product Name	CBX8 (12C7) Monoclonal Antibody
Applications	WB
Reactivity	Human
Specifications
Conjugation	Unconjugated
Host	Mouse
Source	This CBX8 antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between amino acids from the C-terminal region of human CBX8.
Clonality	Monoclonal
Clone #	12C7
Isotype	IgG1
Concentration	0.5ug/ul
Purification	Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition	Store at -20C for 12 months.
Target
Gene ID	57332
Swiss Prot	Q9HC52
Synonyms	PC3; RC1; Chromobox protein homolog 8; Polycomb 3 homolog; hPc3; Rectachrome 1; CBX8
Background	Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
Application Dilution
WB	1:300-5000