PIN1 Monoclonal Antibody

$Lane 1: Mouse Heart tissue lysates probed with PIN1 Monoclonal Antibody, Unconjugated (bsm-51514M) at 1:1000 dilution and 4\u00b0C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37\u02daC.$

Lane 1: Mouse Heart tissue lysates probed with PIN1 Monoclonal Antibody, Unconjugated (bsm-51514M) at 1:1000 dilution and 4\u00b0C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37\u02daC.

Applications

Reactivity

Mouse

Predicted Reactivity

Human
Cow

Overview
Catalog #	bsm-51514m
Product Name	PIN1 Monoclonal Antibody
Applications	WB
Reactivity	Mouse
Predicted Reactivity	Human, Cow
Specifications
Conjugation	Unconjugated
Host	Mouse
Source	Recombinant human UBL5 (Fragment) (His-tagged).
Clonality	Monoclonal
Clone #	F12S3
Isotype	IgG1
Concentration	0.5ug/ul
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition	Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID	5300
Swiss Prot	Q13526
Subcellular location	Cytoplasm, Nucleus
Synonyms	DOD; NIMA interacting 1; Peptidyl prolyl cis trans isomerase NIMA interacting 1; Peptidyl prolyl cis/trans isomerase NIMA interacting; Pin 1; PPIase Pin1; Prolyl isomerase; Protein (peptidylprolyl cis/trans isomerase) NIMA interacting 1; Protein NIMA interacting 1; Rotamase Pin1; UBL 5; UBL5; PIN1_HUMAN.
Background	Essential PPIase that regulates mitosis presumably byinteracting with NIMA and attenuating its mitosis-promotingactivity. Displays a preference for an acidic residue N-terminal tothe isomerized proline bond. Catalyzes pSer/Thr-Pro cis/transisomerizations. Down-regulates kinase activity of BTK. Cantransactivate multiple oncogenes and induce centrosomeamplification, chromosome instability and cell transformation.Required for the efficient dephosphorylation and recycling of RAF1after mitogen activation.
Application Dilution
WB	=1:500-2000