Glucocorticoid receptor Monoclonal Antibody

$Lane 1: Hela cell lysates; Lane 2: A549 cell lysates; Lane 3: CCRF-CEM cell lysates; Lane 4: CHO cell lysates probed with Glucocorticoid receptor Monoclonal Antibody, Unconjugated (bsm-51750M) at 1:2000 dilution and 4\u02daC overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37\u02daC.$

Lane 1: Hela cell lysates; Lane 2: A549 cell lysates; Lane 3: CCRF-CEM cell lysates; Lane 4: CHO cell lysates probed with Glucocorticoid receptor Monoclonal Antibody, Unconjugated (bsm-51750M) at 1:2000 dilution and 4\u02daC overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37\u02daC.

$Lane 1: DU145 cell lysates; Lane 2: U-251MG cell lysates probed with Glucocorticoid receptor Monoclonal Antibody, Unconjugated (bsm-51750M) at 1:2000 dilution and 4\u02daC overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37\u02daC.$

Lane 1: DU145 cell lysates; Lane 2: U-251MG cell lysates probed with Glucocorticoid receptor Monoclonal Antibody, Unconjugated (bsm-51750M) at 1:2000 dilution and 4\u02daC overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37\u02daC.

Applications

Reactivity

Human
Hamster

Predicted Reactivity

Mouse

Overview
Catalog #	bsm-51750m
Product Name	Glucocorticoid receptor Monoclonal Antibody
Applications	WB
Reactivity	Human, Hamster
Predicted Reactivity	Mouse
Specifications
Conjugation	Unconjugated
Host	Mouse
Source	Recombinant human Glucocorticoid receptor.
Clonality	Monoclonal
Clone #	T6R7
Concentration	0.5ug/ul
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition	Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID	2908
Swiss Prot	P04150
Subcellular location	Cytoplasm, Nucleus
Synonyms	NR3C1; GCR_HUMAN; Glucocorticoid receptor isoform alpha; GCCR; GCR; GR; GRL; Grl1; Nuclear receptor subfamily 3 group C member 1; Glucocorticoid receptor lymphocyte.
Background	Receptor for glucocorticoids (GC). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE) and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Could act as a coactivator for STAT5-dependent transcription upon growth hormone (GH) stimulation and could reveal an essential role of hepatic GR in the control of body growth. Involved in chromatin remodeling. Plays a significant role in transactivation. Involved in nuclear translocation.
Application Dilution
WB	=1:500-2000