| Overview |
| bsm-52087r-bf555-100ul |
| HDAC7 Recombinant Antibody, AbBy Fluor-555 Conjugated |
| WB, IF, Flow-Cyt |
| Human, Mouse, Rat |
| Specifications |
| AbBy Fluor-555 |
| Rabbit |
| Recombinant human HDAC7 protein, around N-terminal 150aa. |
| Monoclonal |
| 3H7 |
| IgG |
| Lot dependent |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 51564 |
| Q8WUI4 |
| Histone deacetylase 7; HDAC7 |
| Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer factors such as MEF2A, MEF2B and MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors (By similarity). May be involved in Epstein-Barr virus (EBV) latency, possibly by repressing the viral BZLF1 gene. Positively regulates the transcriptional repressor activity of FOXP3 (PubMed:17360565). |
| Application Dilution |
| WB |
1:300-5000 |
| IF |
|
| Flow-Cyt |
1ug/Test |
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