FTO (Fat mass and obesity related protein) Antibody
Applications
Reactivity
Predicted Reactivity
| Overview | |
| Catalog # | bsm-70094M |
| Product Name | FTO (Fat mass and obesity related protein) Antibody |
| Applications |
WB
|
| Specificity | Specific for endogenous levels of the ~58 kDa FTO protein. |
| Reactivity | Human, Mouse, Rat |
| Predicted Reactivity | Dog, Bovine, Sheep, Non-Human Primate |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Mouse |
| Source | Synthetic peptide corresponding to amino acid residues from the N-terminal region of rat FTO, conjugated to keyhole limpet hemocyanin (KLH). |
| Clonality | Monoclonal |
| Clone # | 5-2H10 |
| Isotype | IgG2a |
| Concentration | Lot Dependent |
| Purification | Purified by Protein G. |
| Storage Buffer | 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 g per ml BSA and 50% glycerol. |
| Storage Condition | Storage at -20C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20C. |
| Target | |
| Gene ID | 79068 |
| Swiss Prot | Q9C0B1 |
| Synonyms | AlkB homolog 9 antibody, ALKBH9 antibody, Alpha-ketoglutarate-dependent dioxygenase FTO antibody, AW743446 antibody, Fat mass and obesity-associated protein antibody, FATSO, MOUSE, HOMOLOG OF antibody, Fto antibody, FTO_HUMAN antibody, GDFD antibody, KIAA1752 antibody, mKIAA1752 antibody, Protein fatso antibody |
| Background | The FTO gene is the most robust gene for common obesity characterized to date. FTO gene expression has been found to be significantly upregulated in the hypothalamus of rats after food deprivation and strongly negatively correlated with the expression of orexin peptide which is involved in the stimulation of food intake (Fredricksson R et al., 2008). Deletion analysis of FTO gene in mice showed that FTO is functionally involved in the control of both energy intake and energy expenditure (Fischer J et al., 2009). |
| Application Dilution | |
| WB | 1:300-5000 |