FMR1 (8C2) Monoclonal Antibody


  • WB


  • Human
Catalog # bsm-51162M
Product Name FMR1 (8C2) Monoclonal Antibody
Applications WB
Reactivity Human
Conjugation Unconjugated
Host Mouse
Source This FMR1 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 20-48 amino acids from human FMR1.
Clonality Monoclonal
Clone # 8C2
Isotype IgM
Concentration 0.5ug/ul
Purification Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C for 12 months.
Gene ID 2332
Swiss Prot Q06787
Synonyms POF; FMRP; POF1; FRAXA; Synaptic functional regulator FMR1; Fragile X mental retardation protein 1; Protein FMR-1; FMR1
Background The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene.
Application Dilution
WB 1:300-5000