|Cytochrome C Polyclonal Antibody, HRP Conjugated
|WB, ELISA, IHC-P, IHC-F
|Human, Mouse, Rat, Chicken, Rabbit
|Cow, Pig, Horse, Guinea Pig
|KLH conjugated synthetic peptide derived from human Cytochrome C
|Purified by Protein A.
|Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
|Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
|Cytoplasm, Cell membrane
|CYC; HCS; THC4; Cytochrome c; CYCS
|Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.