IDE Polyclonal Antibody, Biotin Conjugated

Applications

  • IHC-P

Reactivity

  • Human
  • Mouse
  • Rat
Overview
Catalog # bs-0018R-Biotin
Product Name IDE Polyclonal Antibody, Biotin Conjugated
Applications IHC-P
Reactivity Human, Mouse, Rat
Specifications
Conjugation Biotin
Host Rabbit
Source KLH conjugated synthetic peptide derived from human IDE
Immunogen Range 514-564/1019
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.
Target
Gene ID 3416
Swiss Prot P14735
Subcellular location Cytoplasm, Secreted, Cell membrane
Synonyms INSULYSIN; Insulin-degrading enzyme; Abeta-degrading protease; Insulin protease; Insulinase; IDE
Background Plays a role in the cellular breakdown of insulin, IAPP, glucagon, bradykinin, kallidin and other peptides, and thereby plays a role in intercellular peptide signaling. Degrades amyloid formed by APP and IAPP. May play a role in the degradation and clearance of naturally secreted amyloid beta-protein by neurons and microglia.
Application Dilution
IHC-P 1:500-1000