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    IDE Polyclonal Antibody, Cy5 Conjugated

    Overview
    Catalog # bs-0018R-Cy5
    Product Name IDE Polyclonal Antibody, Cy5 Conjugated
    Applications IF(IHC-P)
    Reactivity Human, Mouse, Rat
    Specifications
    Conjugation Cy5
    Host Rabbit
    Source KLH conjugated synthetic peptide derived from human IDE
    Immunogen Range 514-564/1019
    Clonality Polyclonal
    Isotype IgG
    Concentration 1ug/ul
    Purification Purified by Protein A.
    Storage Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
    Target
    Gene ID 3416
    Swiss Prot P14735
    Subcellular location Cytoplasm, Secreted, Cell membrane
    Synonyms INSULYSIN; Insulin-degrading enzyme; Abeta-degrading protease; Insulin protease; Insulinase; IDE
    Background Plays a role in the cellular breakdown of insulin, IAPP, glucagon, bradykinin, kallidin and other peptides, and thereby plays a role in intercellular peptide signaling. Degrades amyloid formed by APP and IAPP. May play a role in the degradation and clearance of naturally secreted amyloid beta-protein by neurons and microglia.