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    GSK-3 beta (NT) Polyclonal Antibody

    Description:
    Applications:
    • WB
    • IHC-P
    • IF(IHC-P)
    Overview
    Catalog # bs-0023M
    Product Name GSK-3 beta (NT) Polyclonal Antibody
    Applications WB, IHC-P, IF(IHC-P)
    Reactivity Human, Rat
    Specifications
    Conjugation Unconjugated
    Host Mouse
    Source KLH conjugated synthetic peptide derived from human GSK-3 Beta
    Immunogen Range 1-50/420
    Clonality Polyclonal
    Isotype IgG
    Concentration 1ug/ul
    Purification Purified by Protein A.
    Storage Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.
    Target
    Gene ID 2932
    Swiss Prot P49841
    Subcellular location Cytoplasm, Nucleus, Cell membrane
    Synonyms Glycogen synthase kinase-3 beta; GSK-3 beta; Serine/threonine-protein kinase GSK3B; GSK3B
    Background The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]
    Applications
    Application Dilution
    WB 1:300-1000
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200