0 Cart
Added to Cart
    You have items in your cart
    You have 1 item in your cart
    Total
    Check Out Continue Shopping
    `

    Caspase-9 Polyclonal Antibody, Cy7 Conjugated

    Overview
    Catalog # bs-0050R-Cy7
    Product Name Caspase-9 Polyclonal Antibody, Cy7 Conjugated
    Applications IF(IHC-P)
    Reactivity Human
    Specifications
    Conjugation Cy7
    Host Rabbit
    Source KLH conjugated synthetic peptide derived from human Caspase-9 subunit p35
    Immunogen Range 280-330/416
    Clonality Polyclonal
    Isotype IgG
    Concentration 1ug/ul
    Purification Purified by Protein A.
    Storage Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
    Target
    Gene ID 842
    Swiss Prot P55211
    Subcellular location Intracellular
    Synonyms MCH6; APAF3; APAF-3; PPP1R56; ICE-LAP6; Caspase-9; CASP-9; Apoptotic protease Mch-6; Apoptotic protease-activating factor 3; ICE-like apoptotic protease 6; CASP9
    Background Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.