Overview |
bs-0059R-HRP |
APAF1 Polyclonal Antibody, HRP Conjugated |
ELISA, IHC-P, IHC-F |
Human, Mouse, Rat |
Dog, Cow, Horse, Chicken |
Specifications |
HRP |
Rabbit |
KLH conjugated synthetic peptide derived from human Apaf-1 |
13-80/1248 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
317 |
O14727 |
Cytoplasm |
CED4; APAF-1; Apoptotic protease-activating factor 1; APAF1; KIAA0413 |
Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis. |
Application Dilution |
ELISA |
1:500-1000 |
IHC-P |
1:200-400 |
IHC-F |
1:100-500 |