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    CD20 Polyclonal Antibody, FITC Conjugated

    Overview
    Catalog # bs-0080R-FITC
    Product Name CD20 Polyclonal Antibody, FITC Conjugated
    Applications IF(IHC-P)
    Reactivity Human, Mouse, Rat
    Specifications
    Conjugation FITC
    Host Rabbit
    Source KLH conjugated synthetic peptide derived from human CD20
    Immunogen Range 240-290/297
    Clonality Polyclonal
    Isotype IgG
    Concentration 1ug/ul
    Purification Purified by Protein A.
    Storage Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
    Target
    Gene ID 931
    Swiss Prot P11836
    Subcellular location Cytoplasm
    Synonyms B1; S7; Bp35; CD2; CVID5; MS4A2; LEU-16; B-lymphocyte antigen CD2; B-lymphocyte surface antigen B1; Leukocyte surface antigen Leu-16; Membrane-spanning 4-domains subfamily A member 1; MS4A1
    Background B lymphocytes marker CD20 is a non glycosylated protein with a molecular weight of 35 or 37 kDa depending on the degree of phosphorylation. Although not a member of the tetraspanin superfamily of cell surface receptors, it crosses the cell membrane four times. The CD20 antigen is present on human pre B lymphocytes and on B lymphocytes at all stages of maturation, except on plasma cells. Low level expression of the CD20 antigen has been detected on normal T lymphocytes. The CD20 molecule is involved in regulation of B cell differentiation, presumably via its reported function as a Ca++ channel subunit.