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Bax Polyclonal Antibody, Biotin Conjugated

Applications

  • WB
  • ELISA
  • IHC-P
  • IHC-F
  • IP

Reactivity

  • Human
  • Mouse
  • Rat
  • Bovine
  • Pig
  • Chicken
  • Rabbit
  • Zebrafish

Predicted Reactivity

  • Dog
  • Cow
  • Sheep
Overview
Catalog # bs-0127R-Biotin
Product Name Bax Polyclonal Antibody, Biotin Conjugated
Applications WB, ELISA, IHC-P, IHC-F, IP
Reactivity Human, Mouse, Rat, Bovine, Pig, Chicken, Rabbit, Zebrafish
Predicted Reactivity Dog, Cow, Sheep
Specifications
Conjugation Biotin
Host Rabbit
Source KLH conjugated synthetic peptide derived from human Bax
Immunogen Range 84-175/192
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C for 12 months.
Target
Gene ID 581
Swiss Prot Q07812
Subcellular location Cytoplasm, Cell membrane
Synonyms BCL2L4; Apoptosis regulator BAX; Bcl-2-like protein 4; Bcl2-L-4; BAX
Background Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.
Application Dilution
WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IP 1-2ug