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    Nociceptin receptor Polyclonal Antibody, Cy5 Conjugated

    Description:
    Applications:
    • IF(IHC-P)
    Overview
    Catalog # bs-0181R-Cy5
    Product Name Nociceptin receptor Polyclonal Antibody, Cy5 Conjugated
    Applications IF(IHC-P)
    Reactivity Human, Mouse, Rat
    Specifications
    Conjugation Cy5
    Host Rabbit
    Source KLH conjugated synthetic peptide derived from mouse Nociceptin receptor
    Immunogen Range 1-40/367
    Clonality Polyclonal
    Isotype IgG
    Concentration 1ug/ul
    Purification Purified by Protein A.
    Storage Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
    Target
    Gene ID 18389
    Swiss Prot P35377
    Subcellular location Extracellular
    Synonyms KOR3; ORGC; ORL1; Oprl; XOR1; morc; KOR-3; LC132; MOR-C; Nociceptin receptor; K3 opiate receptor; Kappa-type 3 opioid receptor; Orphanin FQ receptor; Oprl1; Oor
    Background G-protein coupled opioid receptor that functions as receptor for the endogenous neuropeptide nociceptin. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling via G proteins mediates inhibition of adenylate cyclase activity and calcium channel activity. Arrestins modulate signaling via G proteins and mediate the activation of alternative signaling pathways that lead to the activation of MAP kinases. Plays a role in modulating nociception and the perception of pain. Plays a role in the regulation of locomotor activity by the neuropeptide nociceptin.
    Applications
    Application Dilution
    IF(IHC-P) 1:50-200