Overview |
bs-0215R-HRP |
CD95 Polyclonal Antibody, HRP Conjugated |
ELISA, IHC-P, IHC-F |
Human, Rat |
Mouse |
Specifications |
HRP |
Rabbit |
KLH conjugated synthetic peptide derived from mouse FAS |
35-110/327 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% Gentamicin. |
Store at 4°C for 12 months. |
Target |
14102 |
P25446 |
Secreted, Cell membrane |
lpr; APO1; APT1; CD95; TNFR6; Tnfrsf6; AI196731; Tumor necrosis factor receptor superfamily member 6; Apo-1 antigen; Apoptosis-mediating surface antigen FAS; FASLG receptor; Fas |
Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both (By similarity). |
Application Dilution |
ELISA |
1:500-1000 |
IHC-P |
1:200-400 |
IHC-F |
1:100-500 |