IGF1R Polyclonal Antibody

Applications

  • WB
  • FCM
  • IHC-P
  • IF(IHC-P)

Reactivity

  • Human
  • Mouse
  • Rat
Overview
Catalog # bs-0227R
Product Name IGF1R Polyclonal Antibody
Applications WB, FCM, IHC-P, IF(IHC-P)
Reactivity Human, Mouse, Rat
Specifications
Conjugation Unconjugated
Host Rabbit
Source KLH conjugated synthetic peptide derived from human IGF-1R alpha chain
Immunogen Range 260-290/1367
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.
Target
Gene ID 3480
Swiss Prot P08069
Subcellular location Extracellular
Synonyms IGFR; CD221; IGFIR; JTK13; Insulin-like growth factor 1 receptor; Insulin-like growth factor I receptor; IGF-I receptor; IGF1R
Background When present in a hybrid receptor with INSR, binds IGF1. PubMed:12138094 shows that hybrid receptors composed of IGF1R and INSR isoform Long are activated with a high affinity by IGF1, with low affinity by IGF2 and not significantly activated by insulin, and that hybrid receptors composed of IGF1R and INSR isoform Short are activated by IGF1, IGF2 and insulin. In contrast, PubMed:16831875 shows that hybrid receptors composed of IGF1R and INSR isoform Long and hybrid receptors composed of IGF1R and INSR isoform Short have similar binding characteristics, both bind IGF1 and have a low affinity for insulin.
Application Dilution
WB 1:300-1000
FCM 1:20-100
IHC-P 1:200-400
IF(IHC-P) 1:50-200