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    HSP70 1A/1B Polyclonal Antibody, FITC Conjugated

    Overview
    Catalog # bs-0244R-FITC
    Product Name HSP70 1A/1B Polyclonal Antibody, FITC Conjugated
    Applications IF(IHC-P)
    Reactivity Human, Mouse, Rat
    Specifications
    Conjugation FITC
    Host Rabbit
    Source KLH conjugated synthetic peptide derived from human HSP70 1A/1B
    Clonality Polyclonal
    Isotype IgG
    Concentration 1ug/ul
    Purification Purified by Protein A.
    Storage Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
    Target
    Gene ID 3303
    Swiss Prot P08107
    Subcellular location Cytoplasm
    Synonyms HSP72; HSPA1; HSP70I; HSP70-1; HSP70-1A; HEL-S-103; Heat shock 70 kDa protein 1A/1B; Heat shock 70 kDa protein 1/2; HSP70-1/HSP70-2; HSP70.1/HSP70.2; HSPA1A; HSX70
    Background In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. In case of rotavirus A infection, serves as a post-attachment receptor for the virus to facilitate entry into the cell.