SSB Polyclonal Antibody, Biotin Conjugated

Applications

  • IHC-P
  • IHC-F

Predicted Reactivity

  • Human
Overview
Catalog # bs-0276R-Biotin
Product Name SSB Polyclonal Antibody, Biotin Conjugated
Applications IHC-P, IHC-F
Predicted Reactivity Human
Specifications
Conjugation Biotin
Host Rabbit
Source KLH conjugated synthetic peptide derived from human SSB
Immunogen Range 201-300/408
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C for 12 months.
Target
Gene ID 6741
Subcellular location Nucleus
Synonyms SSB; Lupus La protein homolog; La ribonucleoprotein; La autoantigen homolog; Sjogren syndrome type B antigen; LA_HUMAN.
Background Lupus La protein (Sjogren syndrome type B antigen) (SS-B) (La ribonucleoprotein) (La autoantigen) plays a role in the transcription of RNA polymerase III. It is most probably a transcription termination factor. Binds to the 3' termini of virtually all nascent polymerase III transcripts. It is associated with precursor forms of RNA polymerase III transcripts including tRNA and 4.5S, 5S, 7S, and 7-2 RNAs. The phosphorylation sites are at the C-terminal part of the protein. Sera from patients with systemic lupus erythematosus(SLE) often contain that react with the normal cellular La protein as if this antigen was foreign.
Application Dilution
IHC-P 1:100-500
IHC-F 1:100-500