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    MBP Polyclonal Antibody, Biotin Conjugated

    Description:
    Applications:
    • WB
    • IHC-P
    • IHC-F
    Overview
    Catalog # bs-0380R-Biotin
    Product Name MBP Polyclonal Antibody, Biotin Conjugated
    Applications WB, IHC-P, IHC-F
    Reactivity Human, Mouse, Rat
    Specifications
    Conjugation Biotin
    Host Rabbit
    Source KLH conjugated synthetic peptide derived from Guinea Pig MBP
    Immunogen Range 45-87/167
    Clonality Polyclonal
    Isotype IgG
    Concentration 1ug/ul
    Purification Purified by Protein A.
    Storage Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
    Target
    Subcellular location Cytoplasm
    Synonyms MBP_CAVPO;Myelin Basic Protein; Myelin basic protien; GDB; Golli MBP; Hemopoietic MBP; HMBPR; HUGO; MBP; MGC99675; MLD; Myelin A1 Protein; Myelin Deficient; Myelin Membrane Encephalitogenic Protein; SHI; Shiverer; SP
    Background Oligodendrocyte Marker The classic group of Myelin basic protein (MBP) isoforms (isoforms 4 to 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non classic group of MBP isoforms (isoforms 1 to 3/Golli MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T cells and neural cells. Differential splicing events combined to optional posttranslational modifications give a wide spectrum of isomers, each of them having maybe a specialized function.
    Applications
    Application Dilution
    WB 1:100-1000
    IHC-P 1:100-500
    IHC-F 1:100-500