Recombinant human CRP protein, C-His
Applications
Reactivity
| Overview | |
| Catalog # | bs-0391p-1mg |
| Product Name | Recombinant human CRP protein, C-His |
| Applications |
ELISA
|
| Reactivity | Others |
| Specifications | |
| Conjugation | Unconjugated |
| Source | Recombinant human CRP protein, C-His protein is expressed in E.coli with C-His. It contains the amino acid sequence of 19-224/224. |
| Storage Buffer | 0.01M TBS(pH7.4) |
| Storage Condition | The product should be stored at -70°C or -20°C. |
| Target | |
| Gene ID | 1401 |
| Swiss Prot | P02741 |
| Background | C Reactive Protein is a major acute phase reactant synthesized primarily in the liver hepatocytes. It is a pentraxin (cyclic pentameric protein) compound of five identical nonglycosylated subunits of 206 amino acids each (m.w. 24 kDa), that are bound noncovalently to form the physiologic CRP molecule (m.w. 117.5 kDa). C Reactive Protein mediates activities associated with preimmune nonspecific host resistance. It is opsonic, an initiator of the classical complement cascade and an activator of monocytes/macrophages. CRP also binds to several nuclear components including chromatin, histones and snRNP, suggesting that it may play a role as a scavenger during cell necrosis. Studies have revealed that among other markers of inflammation, CRP shows the strongest association with cardiovascular events. Many clinical studies demonstrated that coronary mortality among patients with unstable angina and elevated CRP is significantly higher comparing with the patients without elevated CRP. Measurements of C reactive protein (hsCRP) in the patients with ischemic heart disease provide a novel method for detecting individuals at high risk of plaque rupture. |
Frequently asked questions
Which applications is Recombinant human CRP protein, C-His (bs-0391P) validated for, and at what dilution?
bs-0391P is validated for ELISA.
How should bs-0391P be stored?
The product should be stored at -70°C or -20°C. Storage buffer: 0.01M TBS(pH7.4)
How is Recombinant human CRP protein, C-His (bs-0391P) produced?
Recombinant human CRP protein, C-His protein is expressed in E.coli with C-His. It contains the amino acid sequence of 19-224/224.