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DR3 Polyclonal Antibody, AbBy Fluor-488 Conjugated

Applications

  • WB
  • IF(IHC-P)
  • IF(IHC-F)
  • IF(ICC)

Reactivity

  • Human
  • Mouse
  • Rat
Overview
Catalog # bs-0421R-BF488
Product Name DR3 Polyclonal Antibody, AbBy Fluor-488 Conjugated
Applications
WB IF(IHC-P) IF(IHC-F) IF(ICC)
Reactivity Human, Mouse, Rat
Specifications
Conjugation AbBy Fluor-488
Host Rabbit
Source KLH conjugated synthetic peptide derived from human DR3
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 8718
Swiss Prot Q93038
Subcellular location Secreted, Cell membrane
Synonyms DR3; TR3; DDR3; LARD; APO-3; TRAMP; WSL-1; WSL-LR; TNFRSF12; Tumor necrosis factor receptor superfamily member 25; Apoptosis-inducing receptor AIR; Apoptosis-mediating receptor DR3; Apoptosis-mediating receptor TRAMP; Death receptor 3; Lymphocyte-associated receptor of death; Protein WSL; Protein WSL-1; TNFRSF25; APO3; WSL; WSL1; UNQ455/PRO779
Background Receptor for TNFSF12/APO3L/TWEAK. Interacts directly with the adapter TRADD. Mediates activation of NF-kappa-B and induces apoptosis. May play a role in regulating lymphocyte homeostasis.
Application Dilution
WB 1:300-5000
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Frequently asked questions

Which applications is DR3 Polyclonal Antibody, AbBy Fluor-488 Conjugated (bs-0421R-BF488) validated for, and at what dilution?

bs-0421R-BF488 is validated for WB (1:300-5000); IF(IHC-P) (1:50-200); IF(IHC-F) (1:50-200); IF(ICC) (1:50-200). These are recommended starting dilutions; optimal dilutions should be determined by the end user.

Which species does DR3 Polyclonal Antibody, AbBy Fluor-488 Conjugated (bs-0421R-BF488) react with?

Tested reactivity: Human, Mouse, Rat.

How should bs-0421R-BF488 be stored?

Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

What immunogen was used to raise DR3 Polyclonal Antibody, AbBy Fluor-488 Conjugated (bs-0421R-BF488)?

KLH conjugated synthetic peptide derived from human DR3

What are the excitation and emission wavelengths of the AbBy Fluor-488 conjugate (bs-0421R-BF488)?

AbBy Fluor-488 on bs-0421R-BF488: excitation / emission 499nm/519nm.