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DISC1 (CT) Polyclonal Antibody, Cy3 Conjugated

Applications

  • IF(IHC-P)
  • IF(IHC-F)
  • IF(ICC)

Reactivity

  • Human
Overview
Catalog # bs-0430r-cy3-100uL
Product Name DISC1 (CT) Polyclonal Antibody, Cy3 Conjugated
Applications
IF(IHC-P) IF(IHC-F) IF(ICC)
Reactivity Human
Specifications
Conjugation Cy3
Host Rabbit
Source KLH conjugated synthetic peptide derived from human DISC1
Immunogen Range 761-832/854
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 27185
Swiss Prot Q9NRI5
Subcellular location Cytoplasm, Cell membrane
Synonyms disrupted in schizophrenia1; C1orf136; KIAA0457; RP4-730B13.1; SCZD9; DISC1; DISC1_HUMAN.
Background This gene encodes a protein with multiple coiled coil motifs which is located in the nucleus, cytoplasm and mitochondria. The protein is involved in neurite outgrowth and cortical development through its interaction with other proteins. This gene is disrupted in a t(1;11)(q42.1;q14.3) translocation which segregates with schizophrenia and related psychiatric disorders in a large Scottish family. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].
Application Dilution
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Frequently asked questions

Which applications is DISC1 (CT) Polyclonal Antibody, Cy3 Conjugated (bs-0430R-Cy3) validated for, and at what dilution?

bs-0430R-Cy3 is validated for IF(IHC-P) (1:50-200); IF(IHC-F) (1:50-200); IF(ICC) (1:50-200). These are recommended starting dilutions; optimal dilutions should be determined by the end user.

Which species does DISC1 (CT) Polyclonal Antibody, Cy3 Conjugated (bs-0430R-Cy3) react with?

Tested reactivity: Human.

How should bs-0430R-Cy3 be stored?

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

What immunogen was used to raise DISC1 (CT) Polyclonal Antibody, Cy3 Conjugated (bs-0430R-Cy3)?

KLH conjugated synthetic peptide derived from human DISC1 Immunogen range: 761-832/854.

What are the excitation and emission wavelengths of the Cy3 conjugate (bs-0430R-Cy3)?

Cy3 on bs-0430R-Cy3: excitation / emission 512,550nm/570,615nm.

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