Slc22A17 Polyclonal Antibody, PE-Cy5 Conjugated
Applications
Reactivity
Predicted Reactivity
| Overview | |
| Catalog # | bs-0444R-PE-Cy5 |
| Product Name | Slc22A17 Polyclonal Antibody, PE-Cy5 Conjugated |
| Applications |
WB
|
| Reactivity | Human, Rat |
| Predicted Reactivity | Mouse, Dog, Cow, Pig |
| Specifications | |
| Conjugation | PE-Cy5 |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human SLC22A17 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 51310 |
| Swiss Prot | Q8WUG5 |
| Subcellular location | Cell membrane |
| Synonyms | BOCT; BOIT; 24p3R; NGALR; hBOIT; NGALR2; NGALR3; Solute carrier family 22 member 17; 24p3 receptor; Brain-type organic cation transporter; Lipocalin-2 receptor; Neutrophil gelatinase-associated lipocalin receptor; SLC22A17 |
| Background | Cell surface receptor for LCN2 (24p3) that plays a key role in iron homeostasis and transport. Able to bind iron-bound LCN2 (holo-24p3), followed by internalization of holo-24p3 and release of iron, thereby increasing intracellular iron concentration and leading to inhibition of apoptosis. Also binds iron-free LCN2 (apo-24p3), followed by internalization of apo-24p3 and its association with an intracellular siderophore, leading to iron chelation and iron transfer to the extracellular medium, thereby reducing intracellular iron concentration and resulting in apoptosis (By similarity). |
| Application Dilution | |
| WB | 1:300-5000 |
Frequently asked questions
Which applications is Slc22A17 Polyclonal Antibody, PE-Cy5 Conjugated (bs-0444R-PE-Cy5) validated for, and at what dilution?
bs-0444R-PE-Cy5 is validated for WB (1:300-5000). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does Slc22A17 Polyclonal Antibody, PE-Cy5 Conjugated (bs-0444R-PE-Cy5) react with?
Tested reactivity: Human, Rat. Predicted reactivity (expected from sequence homology but not yet tested): Mouse, Dog, Cow, Pig.
How should bs-0444R-PE-Cy5 be stored?
Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise Slc22A17 Polyclonal Antibody, PE-Cy5 Conjugated (bs-0444R-PE-Cy5)?
KLH conjugated synthetic peptide derived from human SLC22A17
What are the excitation and emission wavelengths of the PE-Cy5 conjugate (bs-0444R-PE-Cy5)?
PE-Cy5 on bs-0444R-PE-Cy5: excitation / emission 488nm/670nm.