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RGS2 Polyclonal Antibody, APC Conjugated

Applications

  • IF(IHC-P)
  • IF(IHC-F)
  • IF(ICC)

Reactivity

  • Human
  • Rat

Predicted Reactivity

  • Mouse
  • Cow
  • Sheep
  • Pig
  • Horse
  • Chicken
Overview
Catalog # bs-0492R-APC
Product Name RGS2 Polyclonal Antibody, APC Conjugated
Applications
IF(IHC-P) IF(IHC-F) IF(ICC)
Reactivity Human, Rat
Predicted Reactivity Mouse, Cow, Sheep, Pig, Horse, Chicken
Specifications
Conjugation APC
Host Rabbit
Source KLH conjugated synthetic peptide derived from human RGS2
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 5997
Swiss Prot P41220
Subcellular location Cytoplasm, Nucleus, Cell membrane
Synonyms GS8; Regulator of G-protein signaling 2; RGS2; Cell growth-inhibiting gene 31 protein; G/G1 switch regulatory protein 8; GIG31
Background Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. May play a role in leukemogenesis. Plays a role in negative feedback control pathway for adenylyl cyclase signaling. Binds EIF2B5 and blocks its activity, thereby inhibiting the translation of mRNA into protein.
Application Dilution
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Frequently asked questions

Which applications is RGS2 Polyclonal Antibody, APC Conjugated (bs-0492R-APC) validated for, and at what dilution?

bs-0492R-APC is validated for IF(IHC-P) (1:50-200); IF(IHC-F) (1:50-200); IF(ICC) (1:50-200). These are recommended starting dilutions; optimal dilutions should be determined by the end user.

Which species does RGS2 Polyclonal Antibody, APC Conjugated (bs-0492R-APC) react with?

Tested reactivity: Human, Rat. Predicted reactivity (expected from sequence homology but not yet tested): Mouse, Cow, Sheep, Pig, Horse, Chicken.

How should bs-0492R-APC be stored?

Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

What immunogen was used to raise RGS2 Polyclonal Antibody, APC Conjugated (bs-0492R-APC)?

KLH conjugated synthetic peptide derived from human RGS2

What are the excitation and emission wavelengths of the APC conjugate (bs-0492R-APC)?

APC on bs-0492R-APC: excitation / emission 650nm/660nm.