CD45 Polyclonal Antibody, PE Conjugated

Applications

  • FCM

Reactivity

  • Human
Overview
Catalog # bs-0522R-PE
Product Name CD45 Polyclonal Antibody, PE Conjugated
Applications FCM
Specificity The antibody is predicted to work with Mouse and Rat samples, but with decreased sensitivity compared to human samples.
Reactivity Human
Specifications
Conjugation PE
Host Rabbit
Source KLH conjugated synthetic peptide derived from human CD45
Immunogen Range 1210-1260/1306
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Target
Gene ID 5788
Swiss Prot P08575
Synonyms LCA; LY5; B220; CD45; L-CA; T2; CD45R; GP18; Receptor-type tyrosine-protein phosphatase C; Leukocyte common antigen; PTPRC
Background Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity (By similarity).
Application Dilution
FCM 1:20-100