HMGB1 Polyclonal Antibody, Biotin Conjugated

Applications

  • WB
  • IHC-P
  • IHC-F

Reactivity

  • Human
  • Mouse
  • Rat

Predicted Reactivity

  • Cow
Overview
Catalog # bs-0664R-Biotin
Product Name HMGB1 Polyclonal Antibody, Biotin Conjugated
Applications WB, IHC-P, IHC-F
Reactivity Human, Mouse, Rat
Predicted Reactivity Cow
Specifications
Conjugation Biotin
Host Rabbit
Source KLH conjugated synthetic peptide derived from human HMGB1
Immunogen Range 75-170/215
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C for 12 months.
Target
Gene ID 3146
Swiss Prot P09429
Subcellular location Nucleus
Synonyms HMG1; HMG3; SBP-1; High mobility group protein B1; High mobility group protein 1; HMG-1; HMGB1
Background DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V(D)J recombination by acting as a cofactor of the RAG complex. Acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS). Heparin-binding protein that has a role in the extension of neurite-type cytoplasmic processes in developing cells (By similarity).
Application Dilution
WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500