RANKL Polyclonal Antibody, Biotin Conjugated

Applications

  • WB
  • IHC-P
  • IHC-F

Reactivity

  • Human
  • Mouse
  • Rat
  • Rabbit

Predicted Reactivity

  • Dog
Overview
Catalog # bs-0747R-Biotin
Product Name RANKL Polyclonal Antibody, Biotin Conjugated
Applications WB, IHC-P, IHC-F
Reactivity Human, Mouse, Rat, Rabbit
Predicted Reactivity Dog
Specifications
Conjugation Biotin
Host Rabbit
Source KLH conjugated synthetic peptide derived from human RANKL
Immunogen Range 210-317/317
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C for 12 months.
Target
Gene ID 8600
Swiss Prot O14788
Subcellular location Cytoplasm, Secreted, Cell membrane
Synonyms ODF; OPGL; sOdf; CD254; OPTB2; RANKL; TRANCE; hRANKL2; Tumor necrosis factor ligand superfamily member 11; Osteoclast differentiation factor; Osteoprotegerin ligand; Receptor activator of nuclear factor kappa-B ligand; TNF-related activation-induced cytokine; TNFSF11
Background Cytokine that binds to TNFRSF11B/OPG and to TNFRSF11A/RANK. Osteoclast differentiation and activation factor. Augments the ability of dendritic cells to stimulate naive T-cell proliferation. May be an important regulator of interactions between T-cells and dendritic cells and may play a role in the regulation of the T-cell-dependent immune response. May also play an important role in enhanced bone-resorption in humoral hypercalcemia of malignancy.
Application Dilution
WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500