phospho-AR/Androgen receptor (Ser578) Polyclonal Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bs-0943R |
| Product Name | phospho-AR/Androgen receptor (Ser578) Polyclonal Antibody |
| Applications |
WB
IHC-P
IHC-F
IF
FLOW-CYT
|
| Specificity | This phosphorylation site is homologous to that of Ser558 in Mouse and Ser561 in Rat. |
| Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | KLH conjugated synthetic phosphopeptide derived from human Androgen Receptor around the phosphorylation site of Ser578 [CG(p-S)CK] |
| Immunogen Range | 550-600/919 |
| Modification Site | Ser578 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C for 12 months. |
| Target | |
| Gene ID | 367 |
| Swiss Prot | P10275 |
| Subcellular location | Cytoplasm, Nucleus |
| Synonyms | KD; AIS; TFM; DHTR; SBMA; HYSP1; NR3C4; SMAX1; HUMARA; Androgen receptor; Dihydrotestosterone receptor; Nuclear receptor subfamily 3 group C member 4; AR |
| Background | Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins. Transcription activation is down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3. |
| Application Dilution | |
| WB | IHC-P1:100-500 |
| IHC-P | IFIHC-P1:100-500 |
| IHC-F | |
| IF | |
| Flow-Cyt | |
Frequently asked questions
Which applications is phospho-AR/Androgen receptor (Ser578) Polyclonal Antibody (bs-0943R) validated for, and at what dilution?
bs-0943R is validated for IHC-P (1:100-500); IF(IHC-P) (1:100-500). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does phospho-AR/Androgen receptor (Ser578) Polyclonal Antibody (bs-0943R) react with?
Tested reactivity: Human, Mouse, Rat.
How should bs-0943R be stored?
Store at -20°C for 12 months. Storage buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise phospho-AR/Androgen receptor (Ser578) Polyclonal Antibody (bs-0943R)?
KLH conjugated synthetic phosphopeptide derived from human Androgen Receptor around the phosphorylation site of Ser578 [CG(p-S)CK] Immunogen range: 550-600/919.