CBX5 (Tyr37) Polyclonal Antibody

Applications

  • ELISA
  • IHC-P
  • IHC-F
  • IF(IHC-P)
  • IF(IHC-F)
  • IF(ICC)

Predicted Reactivity

  • Human
  • Mouse
  • Rat
  • Dog
  • Cow
Overview
Catalog # bs-0955R
Product Name CBX5 (Tyr37) Polyclonal Antibody
Applications ELISA, IHC-P, IHC-F, IF(IHC-P), IF(IHC-F), IF(ICC)
Predicted Reactivity Human, Mouse, Rat, Dog, Cow
Specifications
Conjugation Unconjugated
Host Rabbit
Source KLH conjugated synthetic phosphopeptide derived from human CBX5 around the phosphorylation site of Tyr37
Modification Site Tyr37
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID 23468
Subcellular location Nucleus
Synonyms Antigen p25; Cbx 5; Cbx5; CBX5_HUMAN; CG8409; Chromobox homolog 5 Drosophila HP1 alpha; Chromobox homolog 5 HP1 alpha homolog Drosophila; Chromobox homolog 5 HP1 alpha homolog, Drosophila; chromobox homolog 5; HP1 alpha homolog; Chromobox protein homolog 5; Chromobox protein homologue 5; Heterochromatin protein 1 alpha; Heterochromatin protein 1; Heterochromatin protein 1; HP 1; HP 1A; HP1 alpha homolog; HP1; HP1A; HP1Hs alpha; Suvar205; HP1a; HP1Hs-alpha; HP1 alpha; Antigen p25; Heterochromatin protein 1 homolog alpha.
Background This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq].
Application Dilution
ELISA 1:5000-10000
IHC-P 1:100-500
IHC-F 1:100-500
IF(IHC-P) 1:100-500
IF(IHC-F) 1:100-500
IF(ICC) 1:100-500