Transferrin receptor Polyclonal Antibody, Cy7 Conjugated

Applications

  • FCM

Reactivity

  • Human
  • Mouse

Predicted Reactivity

  • Rat
  • Dog
  • Cow
  • Pig
  • Horse
  • Guinea Pig
Overview
Catalog # bs-0988R-Cy7
Product Name Transferrin receptor Polyclonal Antibody, Cy7 Conjugated
Applications FCM
Reactivity Human, Mouse
Predicted Reactivity Rat, Dog, Cow, Pig, Horse, Guinea Pig
Specifications
Conjugation Cy7
Host Rabbit
Source KLH conjugated synthetic peptide derived from human Transferrin receptor
Immunogen Range 621-720/760
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C; for long storage, store at -80°C. Avoid multiple freeze-thaw cycles
Target
Gene ID 7037
Swiss Prot P02786
Subcellular location Cell membrane
Synonyms T9; TR; TFR; p90; CD71; TFR1; TRFR; Transferrin receptor protein 1; TFRC
Background Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site.
Application Dilution
FCM 1:20-100