Nectin 4 Polyclonal Antibody, Biotin Conjugated

Applications

  • WB
  • ELISA

Reactivity

  • Human
  • Mouse

Predicted Reactivity

  • Rat
  • Cow
  • Pig
  • Horse
  • Rabbit
Overview
Catalog # bs-10029R-Biotin
Product Name Nectin 4 Polyclonal Antibody, Biotin Conjugated
Applications WB, ELISA
Reactivity Human, Mouse
Predicted Reactivity Rat, Cow, Pig, Horse, Rabbit
Specifications
Conjugation Biotin
Host Rabbit
Source KLH conjugated synthetic peptide derived from human Nectin 4
Immunogen Range 151-250/510
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C for 12 months.
Target
Gene ID 59341
Subcellular location Secreted, Cell membrane
Synonyms Ig superfamily receptor LNIR; Nectin 4; poliovirus receptor-related 4; PRR4; poliovirus receptor related 4.
Background This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.
Application Dilution
WB 1:300-5000
ELISA 1:500-1000