Nectin 4 Polyclonal Antibody, Biotin Conjugated

Applications

  • WB

Reactivity

  • Human
  • Mouse

Predicted Reactivity

  • Rat
  • Cow
  • Pig
  • Horse
  • Rabbit
Overview
Catalog # bs-10029R-Biotin
Product Name Nectin 4 Polyclonal Antibody, Biotin Conjugated
Applications WB
Reactivity Human, Mouse
Predicted Reactivity Rat, Cow, Pig, Horse, Rabbit
Specifications
Conjugation Biotin
Host Rabbit
Source KLH conjugated synthetic peptide derived from human Nectin 4
Immunogen Range 151-250/510
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C for 12 months.
Target
Gene ID 59341
Subcellular location Secreted, Cell membrane
Synonyms Ig superfamily receptor LNIR; Nectin 4; poliovirus receptor-related 4; PRR4; poliovirus receptor related 4.
Background This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.
Application Dilution
WB 1:300-5000