TLR2 Polyclonal Antibody

Applications

  • WB
  • FCM
  • IHC-P
  • IHC-F
  • IF(ICC)

Reactivity

  • Human
  • Mouse
  • Rat
  • Bovine
  • Pig
  • Sheep

Predicted Reactivity

  • Dog
  • Cow
  • Chicken
Overview
Catalog # bs-1019R
Product Name TLR2 Polyclonal Antibody
Applications WB, FCM, IHC-P, IHC-F, IF(ICC)
Reactivity Human, Mouse, Rat, Bovine, Pig, Sheep
Predicted Reactivity Dog, Cow, Chicken
Specifications
Conjugation Unconjugated
Host Rabbit
Source KLH conjugated synthetic peptide derived from human TLR2 (cytoplasmic domain)
Immunogen Range 701-784/784
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID 7097
Swiss Prot O60603
Subcellular location Cell membrane
Synonyms TIL4; CD282; Toll-like receptor 2; Toll/interleukin-1 receptor-like protein 4; TLR2
Background Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. May also promote apoptosis in response to lipoproteins. Recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR6.
Application Dilution
WB 1:500-2000
FCM 1:100
IHC-P 1:100-500
IHC-F 1:100-500
IF(ICC) 1:100-500