phospho-HDAC5 (Ser498) Polyclonal Antibody, PE Conjugated
Applications
Reactivity
| Overview | |
| Catalog # | bs-10329R-PE |
| Product Name | phospho-HDAC5 (Ser498) Polyclonal Antibody, PE Conjugated |
| Applications |
WB
IF
|
| Reactivity | Human, Mouse, Rat, Bovine |
| Specifications | |
| Conjugation | PE |
| Host | Rabbit |
| Source | KLH conjugated synthetic phosphopeptide derived from human HDAC5 around the phosphorylation site of Ser498 |
| Modification Site | Ser498 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Subcellular location | Nucleus |
| Synonyms | HDAC5Ser498; HDAC5S498; p-HDAC5Ser498; p-HDAC5S498; HD 5; HD5; HDAC 5; Histone deacetylase 5; KIAA0600; NY CO 9; Antigen NY CO 9; FLJ90614; HDAC5_HUMAN; Antigen NY-CO-9. |
| Background | Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]. |
| Application Dilution | |
| WB | |
| IF | |
Frequently asked questions
Which applications is phospho-HDAC5 (Ser498) Polyclonal Antibody, PE Conjugated (bs-10329R-PE) validated for, and at what dilution?
bs-10329R-PE is validated for WB, IF.
Which species does phospho-HDAC5 (Ser498) Polyclonal Antibody, PE Conjugated (bs-10329R-PE) react with?
Tested reactivity: Human, Mouse, Rat, Bovine.
How should bs-10329R-PE be stored?
Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise phospho-HDAC5 (Ser498) Polyclonal Antibody, PE Conjugated (bs-10329R-PE)?
KLH conjugated synthetic phosphopeptide derived from human HDAC5 around the phosphorylation site of Ser498