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Delta Opioid Receptor Polyclonal Antibody, Biotin Conjugated

Applications

  • WB
  • ELISA

Reactivity

  • Human
  • Mouse

Predicted Reactivity

  • Rat
  • Dog
  • Cow
  • Pig
  • Chicken
  • Rabbit
  • GuineaPig
Overview
Catalog # bs-10396R-Biotin
Product Name Delta Opioid Receptor Polyclonal Antibody, Biotin Conjugated
Applications WB, ELISA
Specificity This antibody may also have a weak secondary cross-reaction with Mu-type opioid receptor, which is primarily expressed in the adrenal gland and testis. This is predicted based upon a 79% non-contiguous sequence similarity.
Reactivity Human, Mouse
Predicted Reactivity Rat, Dog, Cow, Pig, Chicken, Rabbit, GuineaPig
Specifications
Conjugation Biotin
Host Rabbit
Source KLH conjugated synthetic peptide derived from human OPRD1
Clonality Polyclonal
Clone # #REF!
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20C for 12 months.
Target
Gene ID 4985
Swiss Prot P41143
Subcellular location Cell membrane
Synonyms OPRD; Delta-type opioid receptor; D-OR-1; DOR-1; OPRD1
Background G-protein coupled receptor that functions as receptor for endogenous enkephalins and for a subset of other opioids. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain and in opiate-mediated analgesia. Plays a role in developing analgesic tolerance to morphine.
Application Dilution
WB 1:300-5000
ELISA 1:500-1000