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B3GALNT1 Polyclonal Antibody

Applications

  • WB
  • ELISA
  • IHC-P
  • IHC-F
  • IF(IHC-P)
  • IF(IHC-F)
  • IF(ICC)
  • ICC

Predicted Reactivity

  • Human
  • Mouse
  • Rat
  • Dog
  • Cow
  • Pig
  • Horse
  • Rabbit
Overview
Catalog # bs-10438R
Product Name B3GALNT1 Polyclonal Antibody
Applications WB, ELISA, IHC-P, IHC-F, IF(IHC-P), IF(IHC-F), IF(ICC), ICC
Predicted Reactivity Human, Mouse, Rat, Dog, Cow, Pig, Horse, Rabbit
Specifications
Conjugation Unconjugated
Host Rabbit
Source KLH conjugated synthetic peptide derived from human B3GALNT1
Immunogen Range 231-331/331
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID 8706
Swiss Prot O75752
Subcellular location Cytoplasm, Cell membrane
Synonyms 3-galactosyltransferase 3; 3-GalNAc-T1; 3-GalTase 3; 3-N-acetylgalactosaminyltransferase 1; 3-N-acetylgalactosaminyltransferase; b3Gal T3; b3Gal-T3; B3galnt1; B3GALT3; B3GL1_HUMAN; Beta 1,3 galactosyltransferase 3; Beta 1,3 GalTase 3; beta 1,3 N acetylgalactosaminyltransferase 1 globoside blood group; Beta 3 GalNAc T1; Beta 3 Gx T3; Beta-1; Beta-3-Gx-T3; beta3Gal T3; Beta3Gal-T3; Beta3GalT3; brainiac1; Galactosylgalactosylglucosylceramide beta D acetyl galactosaminyltransferase; Galactosylgalactosylglucosylceramide beta-D-acetyl-galactosaminyltransferase; galT3; Gb4Cer; GLCT3; GLOB; Globoside synthase; globotriaosylceramide 3 beta N acetylgalactosaminyltransferase; P antibody P antigen synthase; P blood group globoside; P1 antibody UDP Gal:betaGlcNAc beta 1,3 galactosyltransferase 1; UDP Gal:betaGlcNAc beta 1,3 galactosyltransferase, polypeptide 3 Globoside blood group; UDP GalNAc:beta 1,3 N acetylgalactosaminyltransferase 1; UDP GalNAc:betaGlcNAc beta 1,3 galactosaminyltransferase, polypeptide 1 Globoside blood group; UDP N acetylgalactosamine:globotriaosylceramide beta 1,3 N acetylgalactosaminyltransferase; UDP-GalNAc:beta-1; UDP-N-acetylgalactosamine:globotriaosylceramide beta-1
Background This gene is a member of the beta-1,3-galactosyltransferase (beta3GalT) gene family. This family encodes type II membrane-bound glycoproteins with diverse enzymatic functions using different donor substrates (UDP-galactose and UDP-N-acetylglucosamine) and different acceptor sugars (N-acetylglucosamine, galactose, N-acetylgalactosamine). The beta3GalT genes are distantly related to the Drosophila Brainiac gene and have the protein coding sequence contained in a single exon. The beta3GalT proteins also contain conserved sequences not found in the beta4GalT or alpha3GalT proteins. The carbohydrate chains synthesized by these enzymes are designated as type 1, whereas beta4GalT enzymes synthesize type 2 carbohydrate chains. The ratio of type 1:type 2 chains changes during embryogenesis. By sequence similarity, the beta3GalT genes fall into at least two groups: beta3GalT4 and 4 other beta3GalT genes (beta3GalT1-3, beta3GalT5). The encoded protein of this gene does not use N-acetylglucosamine as an acceptor sugar at all. Multiple transcript variants that are alternatively spliced in the 5' UTR have been described; they all encode the same protein.
Application Dilution
WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500