| Overview |
| bs-10489R |
| HHV DNA polymerase catalytic subunit Antibody |
| IHC-P, IF(IHC-P) |
| This antibody will detect both HHV1 and HHV2 DNA polymerase catalytic subunit |
| Virus |
| Specifications |
| Unconjugated |
| Rabbit |
| KLH conjugated synthetic peptide derived from human Human herpesvirus 1 DNA polymerase catalytic subunit |
| 1200-1235/1235 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months. |
| Target |
| DPOL_HHV11; DNA polymerase catalytic subunit; UL30; HHV1gp046. |
| Replicates viral genomic DNA. The replication complex is composed of six viral proteins: the DNA polymerase, processivity factor, primase, primase-associated factor, helicase, and ssDNA-binding protein. Additionally, the polymerase contains an intrinsic ribonuclease H (RNase H) activity that specifically degrades RNA/DNA heteroduplexes or duplex DNA substrates in the 5' to 3' direction. Therefore, it can catalyze the excision of the RNA primers that initiate the synthesis of Okazaki fragments at a replication fork during viral DNA replication. |
| Application Dilution |
| IHC-P |
1:200-400 |
| IF(IHC-P) |
1:50-200 |