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Cathepsin L(heavy chain) Polyclonal Antibody, AbBy Fluor-750 Conjugated

Applications

  • IF(ICC)
  • IF

Reactivity

  • Human
  • Mouse

Predicted Reactivity

  • Rat
Overview
Catalog # bs-10523R-BF750
Product Name Cathepsin L(heavy chain) Polyclonal Antibody, AbBy Fluor-750 Conjugated
Applications IF(ICC), IF
Reactivity Human, Mouse
Predicted Reactivity Rat
Specifications
Conjugation AbBy Fluor-750
Host Rabbit
Source KLH conjugated synthetic peptide derived from mouse Cathepsin L
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 13039
Swiss Prot P06797
Synonyms Cathepsin L; Major Excreted Protein; Cathepsin L1; EC 3.4.22.15; CTSL1; MEP; EC 3.4.22; CATL; CATL1_MOUSE;
Background The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Apr 2012]
Application Dilution
IF(ICC)
IF