GPM6A Polyclonal Antibody

Applications

  • FCM

Reactivity

  • Human
  • Mouse
  • Rat
Overview
Catalog # bs-10757R
Product Name GPM6A Polyclonal Antibody
Applications FCM
Reactivity Human, Mouse, Rat
Specifications
Conjugation Unconjugated
Host Rabbit
Source KLH conjugated synthetic peptide derived from human GPM6A
Immunogen Range 160-200/278
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.
Target
Gene ID 2823
Swiss Prot P51674
Subcellular location Extracellular
Synonyms M6A; GPM6; Neuronal membrane glycoprotein M6-a; GPM6A
Background Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca(2+) influx. May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs); enhances internalization and recycling of mu-type opioid receptor.
Application Dilution
FCM 1:20-100