Recombinant human TNNI3 protein, N-His

Overview
Catalog #	bs-10877p-100ug
Product Name	Recombinant human TNNI3 protein, N-His
Applications	ELISA
Reactivity	Others
Specifications
Conjugation	Unconjugated
Source	Recombinant human TNNI3 protein, N-His protein is expressed in E.coli with N-His. It contains the amino acid sequence of 2-210/210.
Storage Buffer	0.01M TBS(pH7.4)
Storage Condition	The product should be stored at -70°C or -20°C.
Target
Gene ID	7137
Swiss Prot	P19429
Background	Troponin I is a cardiac and skeletal muscle protein useful in the laboratory diagnosis of heart attack. Troponin I is a part of the troponin protein complex, where it binds to actin in thin myofilaments to hold the actin-tropomyosin complex in place. Because of it, myosin cannot bind actin in relaxed muscle. When calcium binds to the troponin C it causes conformational changes which lead to dislocation of troponin I and finally tropomyosin leaves the binding site for myosin on actin leading to contraction of muscle.