Urokinase Polyclonal Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bs-1098r |
| Product Name | Urokinase Polyclonal Antibody |
| Applications |
WB
IHC-P
IHC-F
IF
|
| Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from rat PLAU |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C for 12 months. |
| Target | |
| Gene ID | 5328 |
| Synonyms | Urokinase; ATF; ATF uPA; Plasminogen activator; Plasminogen activator urinary; Plasminogen activator urokinase; PLAU; u PA; U plasminogen activator; UPA; URK; Urokinase plasminogen activator; Urokinase type plasminogen activator; Urokinase type plasminogen activator precursor. |
| Background | Urokinase is a serine protease involved in degradation of the extracellular matrix and possibly tumor cell migration and proliferation. A specific polymorphism in the Urokinase gene may be associated with late onset Alzheimer disease and also with decreased affinity for fibrin binding. This protein converts plasminogen to plasmin by specific cleavage of an Arg Val bond in plasminogen. The proprotein is cleaved at a Lys Ile bond by plasmin to form a two chain derivative in which a single disulfide bond connects the amino terminal A chain to the catalytically active, carboxy terminal B chain. This two chain derivative is also called HMW uPA (high molecular weight uPA). HMW uPA can be further processed into LMW uPA (low molecular weight uPA) by cleavage of chain A into a short chain A (A1) and an amino terminal fragment. LMW uPA is proteolytically active but does not bind to the uPA receptor. |
| Application Dilution | |
| WB | |
| IHC-P | |
| IHC-F | |
| IF | |
Frequently asked questions
Which applications is Urokinase Polyclonal Antibody (bs-1098R) validated for, and at what dilution?
bs-1098R is validated for WB, IHC-P, IHC-F, IF.
Which species does Urokinase Polyclonal Antibody (bs-1098R) react with?
Tested reactivity: Human, Mouse, Rat.
How should bs-1098R be stored?
Store at -20°C for 12 months. Storage buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise Urokinase Polyclonal Antibody (bs-1098R)?
KLH conjugated synthetic peptide derived from rat PLAU