CD36 Polyclonal Antibody, Biotin Conjugated
Applications
Reactivity
| Overview | |
| Catalog # | bs-1100r-biotin-100uL |
| Product Name | CD36 Polyclonal Antibody, Biotin Conjugated |
| Applications |
WB
IHC-P
IHC-F
IP
|
| Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | Biotin |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from mouse CD36 |
| Immunogen Range | 51-150/472 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | Lot Dependent |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C for 12 months. |
| Target | |
| Gene ID | 12491 |
| Swiss Prot | Q08857 |
| Subcellular location | Cell membrane |
| Synonyms | FAT; GPIV; Scarb3; Platelet glycoprotein 4; Glycoprotein IIIb; GPIIIB; PAS IV; PAS-4; Platelet glycoprotein IV; CD36 |
| Background | Binds to collagen, thrombospondin, anionic phospholipids and oxidized low-density lipoprotein (oxLDL). May function as a cell adhesion molecule. Directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes. Binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport (By similarity). Receptor for thombospondins, THBS1 AND THBS2, mediating their antiangiogenic effects (By similarity). As a coreceptor for TLR4-TLR6, promotes inflammation in monocytes/macrophages. Upon ligand binding, such as oxLDL or amyloid-beta 42 binding, rapidly induces the formation of a heterodimer of TLR4 and TLR6, which is internalized and triggers inflammatory signals, leading to the NF-kappa-B-dependent production of CXCL1, CXCL2 and CCL9 cytokines, via MYD88 signaling pathway, and CCL5 cytokine, via TICAM1 signaling pathway, as well as IL1B secretion. |
| Application Dilution | |
| WB | =1:500-2000 |
| IHC-P | IHC-P=1:50-200 |
| IHC-F | IHC-F=1:50-200 |
| IP | IP=1:20-50 |
Frequently asked questions
Which applications is CD36 Polyclonal Antibody, Biotin Conjugated (bs-1100R-Biotin) validated for, and at what dilution?
bs-1100R-Biotin is validated for WB (WB=1:500-2000); IHC-P (IHC-P=1:50-200); IHC-F (IHC-F=1:50-200); IP (IP=1:20-50). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does CD36 Polyclonal Antibody, Biotin Conjugated (bs-1100R-Biotin) react with?
Tested reactivity: Human, Mouse, Rat.
How should bs-1100R-Biotin be stored?
Store at -20°C for 12 months. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise CD36 Polyclonal Antibody, Biotin Conjugated (bs-1100R-Biotin)?
KLH conjugated synthetic peptide derived from mouse CD36 Immunogen range: 51-150/472.