CD36 Polyclonal Antibody
Applications
Reactivity
Predicted Reactivity
| Overview | |
| Catalog # | bs-1100r-20uL |
| Product Name | CD36 Polyclonal Antibody |
| Applications |
WB
IHC-P
IHC-F
IP
IF
FLOW-CYT
|
| Reactivity | Mouse, Rat |
| Predicted Reactivity | Human |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human CD36 |
| Immunogen Range | 51-150/472 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1mg/ml |
| Purification | purified by Protein A. |
| Storage Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles. |
| Target | |
| Gene ID | 948 |
| Swiss Prot | P16671 |
| Subcellular location | Cell membrane |
| Synonyms | BDPLT10; CHDS7; FAT; GP3B; GP4; GPIV; PASIV; SCARB3; GPIIIB; IV; PAS; PAS IV; PAS-4; CD36_HUMAN; CD36; Fatty acid translocase (FAT); Glycoprotein IIIb (GPIIIB); Leukocyte differentiation antigen CD36; Platelet collagen receptor; Platelet glycoprotein IV (GPIV); Thrombospondin receptor; CD36_MOUSE; CD36_RAT; Adipocyte membrane protein; Fatty acid translocase; Fatty acid transport protein; CD36 molecule (CD36 blood group); CD36 antigen (collagen type I receptor, thrombospondin receptor); CD36 molecule (thrombospondin receptor); scavenger receptor class B member 3; Platelet glycoprotein 4 |
| Background | Binds to collagen, thrombospondin, anionic phospholipids and oxidized low-density lipoprotein (oxLDL). May function as a cell adhesion molecule. Directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes. Binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport (By similarity). Receptor for thombospondins, THBS1 AND THBS2, mediating their antiangiogenic effects (By similarity). As a coreceptor for TLR4-TLR6, promotes inflammation in monocytes/macrophages. Upon ligand binding, such as oxLDL or amyloid-beta 42 binding, rapidly induces the formation of a heterodimer of TLR4 and TLR6, which is internalized and triggers inflammatory signals, leading to the NF-kappa-B-dependent production of CXCL1, CXCL2 and CCL9 cytokines, via MYD88 signaling pathway, and CCL5 cytokine, via TICAM1 signaling pathway, as well as IL1B secretion. |
| Application Dilution | |
| WB | =1:500-2000 |
| IHC-P | IHC-P=1:50-200 |
| IHC-F | IHC-F=1:50-200 |
| IP | IP=1:20-50 |
| IF | IF=1:50-200 |
| Flow-Cyt | Flow-Cyt=1ug/Test |
Frequently asked questions
Which applications is CD36 Polyclonal Antibody (bs-1100R) validated for, and at what dilution?
bs-1100R is validated for WB (WB=1:500-2000); IHC-P (IHC-P=1:50-200); IHC-F (IHC-F=1:50-200); IP (IP=1:20-50); IF (IF=1:50-200); Flow-Cyt (Flow-Cyt=1ug/Test). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does CD36 Polyclonal Antibody (bs-1100R) react with?
Tested reactivity: Mouse, Rat. Predicted reactivity (expected from sequence homology but not yet tested): Human.
How should bs-1100R be stored?
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles. Storage buffer: 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise CD36 Polyclonal Antibody (bs-1100R)?
KLH conjugated synthetic peptide derived from human CD36 Immunogen range: 51-150/472.