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procollagen type IIA Polyclonal Antibody

Applications

  • ELISA
  • IHC-P
  • IHC-F
  • IF(IHC-P)
  • IF(IHC-F)
  • IF(ICC)

Reactivity

  • Zebrafish

Predicted Reactivity

  • Human
  • Dog
  • Cow
  • Sheep
  • Pig
  • Chicken
  • Rabbit
  • Guinea Pig
Overview
Catalog # bs-11069R
Product Name procollagen type IIA Polyclonal Antibody
Applications ELISA, IHC-P, IHC-F, IF(IHC-P), IF(IHC-F), IF(ICC)
Reactivity Zebrafish
Predicted Reactivity Human, Dog, Cow, Sheep, Pig, Chicken, Rabbit, Guinea Pig
Specifications
Conjugation Unconjugated
Host Rabbit
Source KLH conjugated synthetic peptide derived from human Collagen II alpha 1
Clonality Polyclonal
Clone # #REF!
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Shipped at 4_. Store at -20_ for one year. Avoid repeated freeze/thaw cycles.
Target
Subcellular location Secreted, Extracellular matrix
Synonyms Collagen II N-terminal propeptide; Collagen II alpha 1; COL2A1; COL2A1 protein; collagen, type II, alpha 1; collagen alpha-1II; type II collagen; alpha-1 type II collagen; alpha1 type II collagen; Col2a1; AOM; Cartilage collagen; COL11A3; Collagen alpha 1II chain precursor; Collagen II alpha 1 polypeptide; Collagen type II alpha 1 primary osteoarthritis spondyloepiphyseal dysplasia congenital; MGC131516; SEDC; Collagen alpha-1II chain; Alpha-1 type II collagen; CO2A1_HUMAN.
Background Collagen type II is the most abundant protein of cartilage matrix. Two isoforms exist and collagen type IIA is involved in early development of cartilage in embryos. The collagen is produced from type II procollagen when two teloterminal propeptides are digested from the precursor and released into the circulation. Procollagen type II N-terminal propeptide is considered a marker of cartilage synthesis and the normal concentration in serum is approximately 30ng/mL.
Application Dilution
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200