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MC4 Receptor Polyclonal Antibody, Biotin Conjugated

Applications

  • ELISA
  • IHC-F

Reactivity

  • Human
  • Mouse
  • Rat
Overview
Catalog # bs-11417R-Biotin
Product Name MC4 Receptor Polyclonal Antibody, Biotin Conjugated
Applications ELISA, IHC-F
Reactivity Human, Mouse, Rat
Specifications
Conjugation Biotin
Host Rabbit
Source KLH conjugated synthetic peptide derived from human MC4 Receptor
Immunogen Range 1-50/332
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C for 12 months.
Target
Gene ID 4160
Swiss Prot P32245
Subcellular location Cell membrane
Synonyms MC4 R; MC4-R; MC4R; MC4R_HUMAN; Melanocortin 4 receptor; Melanocortin receptor 4; MGC126851; MGC138197.
Background The melanocortin family comprises the Alpha-, Beta- and Gamma- melanocyte stimulating hormones (MSH) and adrenocorticotrophin. The receptors for these hormones are seven-transmembrane G protein-coupled proteins that activate adenylyl cyclase. Five melanocortin receptors have been cloned and shown to exhibit different affinities and patterns of expression. MC1-R (MSH-R) is expressed in melanocytes and corticoadrenal tissue. MC2-R is the ACTH receptor and is expressed primarily in the adrenal cortex. MC3-R has been found in specific regions of the brain and is also expressed in placenta and gut. MC4-R is expressed primarily in brain, while MC5-R is expressed at low levels in most tissues.
Application Dilution
ELISA 1:500-1000
IHC-F 1:100-500